Table 4 |
|
|
Gaps in our knowledge related to surrogate selection and model parameters. |
|
|
Gaps |
Recommended action |
|
|
|
|
No quantitative comparisons of spore survival on fomites |
Conduct experiments using steel, laminar, plastic and other surfaces |
|
|
|
|
No quantitative comparisons of spore survival in soil |
Conduct experiments across soil types |
|
|
|
|
No quantitative comparisons of spore survival in buffer/water |
Conduct survival experiments in water or buffer |
|
|
|
|
No long-term studies |
Perform spore survival studies that are over a year long |
|
|
|
|
Only one comparative study examining the effect of heat in various buffers |
Reconfirm results |
|
|
|
|
Only one comparative study with UV |
Reconfirm results |
|
|
|
|
Only a few studies with virulent Bacillus anthracis |
Use virulent B. anthracis and compare directly to potential surrogates |
|
|
|
|
Greenberg et al. Investigative Genetics 2010 1:4 doi:10.1186/2041-2223-1-4 |
|